South Park

South Park is an American adult animated sitcom created by Trey Parker and Matt Stone for the Comedy Central television network. The show revolves around four boys—Stan Marsh, Kyle Broflovski, Eric Cartman, and Kenny McCormick—and their bizarre adventures in and around the titular Colorado town.

Roger Ebert Should Lay Off the Fatty Foods (Season 2, Episode 11)
The boys investigate a mysterious conspiracy centered around the South Park Planetarium and find out that the head of it is using a hypnosis device to bring more people to the the place.

Bebe's Boobs Destroy Society (Season 6, Episode 10)
Bebe Stevens develops breasts and she suddenly becomes the most popular girl in her class amongst the boys while also regressing their sapience to the level of prehistoric humans. She quickly gets sick of the over-attention.

The Return of Chef (Season 10, Episode 1)
After a long hiatus, Chef returns to South Park, but the boys find out that while he was gone, he was brainwashed to become a different person.