Fullmetal Alchemist (2003)

Fullmetal Alchemist (Japanese: 鋼の錬金術師 Hepburn: Hagane no Renkinjutsushi) is an anime series adapted from the manga of the same name by Hiromu Arakawa.

As in the manga, the series follows the adventures of brothers Edward and Alphonse Elric, who are searching for the Philosopher's Stoneso they can regain the bodies they lost in a failed attempt to bring their dead mother back to life. During production, Arakawa requested an original ending that differed from the manga, leading to the series deviating into an original plot halfway through.

The Other Side of the Gate (Episode 49)
Trying to remain young and pure, Dante, the main villain of the series, mind controls Rose to use her a host.

Death (Episode 50)
Rose breaks out her trance once she sees Edward's bloody death.