Eddsworld

Eddsworld is a series of animations, comics, and games created by the late Edd Gould and maintained by his friends and family. Edd and his friends, like Matt Hargreaves, Tord Larsson and Thomas Ridgewell, would have animated counterparts of themselves appear in the various media Edd posted online. Edd's earliest-surviving creation was a short titled Edd, and it was uploaded to Newgrounds on June 6, 2003, the same day he registered.

Trick or threat
Matt gets possessed by a girl and tries to kill Edd. Later, Edd is now possessed and fights Matt much to the girl's amusement. Later, Tom throws out the girl and it's revealed that Tom was already possessed