Miss Sherlock

Miss Sherlock (ミス・シャーロック) is a female-led adaptation of Sir Arthur Conan Doyle's Sherlock Holmes detective stories. The show is primarily set in Tokyo, Japan. It is a co-production between HBO Asia and Hulu Japan. Both the main characters, based on Sherlock Holmes and Dr. John Watson, are played by women, Yuko Takeuchi and Shihori Kanjiya respectively and it is the first major series to cast a woman as Holmes-like detective.

Plot
Miss Sherlock depicts "consulting detective" Sara "Sherlock" Shelly Futaba (Yūko Takeuchi) solving various mysteries in modern-day Tokyo. Sherlock is assisted by her flatmate, Dr. Wato Tachibana (Shihori Kanjiya), a doctor who has recently returned from volunteering medical aid in Syria. Because of Sherlock's keen observational and deduction skills, she is frequently asked by Inspector Gentaro Reimon of the Metropolitan Police to help with cases.

Although the series depicts a variety of crimes and perpetrators, Sherlock must deal with the secret organization, Stella Maris, a hypnotist and mastermind who is behind some of the crimes they solve. Other recurring characters include Kimi Hatano, the landlady where Sherlock lives, and Kento Futaba, the Prime Minister Secretary and Sherlock's older brother.

Episode 08: The Dock
The Metropolitan Police conducts a manhunt for Sherlock, cutting the detective off from her allies and forcing her into hiding as she tries to figure out Wato's whereabouts and Dr. Irikawa's next move. Dr. Irikawa takes Wato to her secret facility known as the Dock and begins brainwashing her to turn her against Sherlock. After having a brief confrontation with Dr. Irikawa and breaking into her office, Sherlock discovers that she intends to locate the specs of a miniature nuclear warhead and have Wato unleash it. Sherlock finds the specs inside the designer's prison cell by revealing plans he'd written on the walls in blood before his death, then obscures the writing so that Dr. Irikawa cannot see it. She agrees to meet Dr. Irikawa on a skyscraper rooftop to exchange the warhead specs for Wato's safe return, but Wato, still under the effects of Irikawa's brainwashing, arrives at the meeting and holds Sherlock at gunpoint. Sherlock manages to talk Wato down long enough for her to hesitate, then tackles Dr. Irikawa over the roof, sending both women falling down the side of the building. Wato deeply mourns Sherlock's supposed death as she moves out of the flat they shared, though the episode ends with Wato being approached from behind by a familiar figure clad in a trench coat and heels.